Preprints have revolutionised scientific publishing by enabling researchers to share their discoveries with the world immediately. However, the sheer volume of preprints being published on a daily basis results in an overwhelming landscape for those eager to keep up with the cutting edge of science.
This is where The Longevist steps in.
Supporting VitaDAO's mission to improve healthspan, we endeavour to spotlight the most groundbreaking longevity studies each quarter. Our editorial team utilises a combination of social listening tools, AI, and an expansive network to forge a shortlist of preprint contenders. Our expert panel of Longevist Curators then vote in a quarterly battle royale to establish the cream of the crop.
In addition to curation, The Longevist fosters a space for collaborative discourse, through our peer review platform - The Longevity Decentralised Review - to seamlessly blend expert insights with user-friendly, advanced technology.
We invite you to join this vibrant community. Dive deep into the latest in longevity science and play a pivotal role in shaping the future narrative of this fascinating field.
Professor of Medicine at National University of Singapore and VU Amsterdam, and founder of Chi Longevity. Her research is driven by her passion to unravel ageing mechanisms and the interaction of ageing and age-related syndromes and diseases, which eventually leads to counteracting interventions. Her research group particularly focuses on intervention studies testing geroprotectors to optimize health and bringing innovations into clinical practice.
Cláudia Cavadas is associate professor at the Faculty of Pharmacy of the University of Coimbra and Group Leader of “Neuroendocrinology and Aging group” at Center for Neuroscience and Cell Biology, University of Coimbra. Investigates the cellular and molecular mechanisms related to hypothalamic functions (feeding, circadian rhythm, sleep , life style) on the ageing process.
Attending ICU physician at UCSF Medical Center and directs a research laboratory at the Parnassus Heights campus. His lab focuses on lung injury and fibrosis, both major health problems for which effective therapies are limited, and is developing novel approaches to the study of cell-cell interactions in the lung--for example, between immune and structural cells.
Studies translational research into human aging with a focus on how immune responses and physical function decline as we get older. Her multidisciplinary research aims to uncover common pathways among the aging process and to develop potential interventions to prevent age-related declines in immune responses and help older adults maintain their independence into late life.
A major contributor in the field of nicotinamide adenine dinucleotide (NAD) metabolism, Brenner discovered the nicotinamide riboside kinase pathway to NAD and developed targeted, quantitative methods for NAD metabolomics. Brenner’s work has uncovered multiple diseases and conditions in which the NAD system comes under attack and in which provision of NR has the potential to improve repair and resiliency. His work has been successfully translated into consumer products, thereby creating and the NAD-boosting industry, and is the subject of over 50 registered clinical trials worldwide.
Group Leader of the Laboratory of Cellular Senescence and Age-related Pathologies at University of Groningen and the European Research Institute for the Biology of Aging (ERIBA). Interested to unravel molecular and cellular mechanisms involved during aging, age-related diseases and cancer, using different types of cellular and in vivo models. His goal is to identify new therapeutic approaches to build more efficient therapies to limit pathology and to extend healthspan.
Junior Group Leader and Head of the Microbiome and Metabolism in Aging Lab at the Leibniz Institute on Aging – Fritz Lipmann Institute in Germany. Her research investigates the significance of the chemical crosstalk between cells, which plays a fundamental role in modulating cellular and tissue function.
Brad is a Primary Care Physician, practicing in Auckland, New Zealand. He has a deep passion for preventative medicine and helping people lead healthy, long lives. He created and hosts a YouTube channel that now has over 185,000 subscribers, which educates people on the latest clinical guidelines and research.
Independent group leader, Metabolism and epigenetics in aging, FBN (Rostock). Interested in the role of the metabolism - epigenetics connectivity during early ageing, response to stress and cognitive impairment. Aiming to pursue novel, preventive therapeutic avenues to increase a healthy human life span.
Prof. David Vilchez’s laboratory is focused on defining the mechanisms underlying protein homeostasis (proteostasis) regulation in stem cells. The final goal is to determine whether intervention of these proteostasis mechanisms slow down aging and protect from the symptoms associated to age-related pathologies by using C. elegans as a model organism.
Head of the Bioengineering Research Group and Bio-AI Laboratory at Cardiff Metropolitan University. His current research focuses on the development of laboratory systems for cryopreservation, and the development of classification and staging systems for age-related pathology within the context of the WHO ICD-11.
Nicholas Tolwinski is an Associate Professor at Duke-NUS Medical School and Yale-NUS College. His laboratory specialises in analysing signal transduction during development and aging in Drosophila. His research applies novel microscopy techniques to model how groups of cells organise into tissues. The laboratory’s primary focus is on Wnt signaling in development and aging.
Jan is an Associate Professor at Yale-NUS. His research aims to elucidate molecular mechanisms of ageing, in particular to understand the role of damage and mitochondria in ageing, to develop ageing clocks, and to test related intervention strategies against ageing and age-dependent diseases.
Group Leader at the Institute for Research on Cancer and Aging, Nice (IRCAN). His laboratory investigates cellular senescence and its interaction with the immune system in the context of aging and cancer with a specific focus on how senescence-specific cell surface molecules could modulate Natural Killer cell mediated immune surveillance.
Cell Biologist researching senescence and ageing at King's College London. Longevity Impetus Grant awardee. VitaDAO Contributor.
Longevity Scientist & AI Engineer who is committed to enhancing humans and advancing civilization. VitaDAO core contributor.
Innovation Lead at the DTx Warehouse, a Champaulimaud Foundation project. VitaDAO contributor. Biotech Startup Advisor. Writer.
Entrepreneur. Growth Hacker. Investor. Longevity advocate. VitaDAO Steward.
Interface designer and web developer with more than 15 years of experience in working on web applications.
An overlay journal to select the most impactful longevity research every quarter.
The Longevist specifically features longevity-focused preprints uploaded to servers such as bioRxiv, medRxiv, and arXiv.
The Longlist - our editorial team compiles a longlist of longevity preprints throughout each annual quarter. We also accept and encourage preprint nominations from our readers, with $VITA prize bounties awarded for the best suggestions.
The Shortlist - at the end of each quarter, our editors whittle down the longlist to create a shortlist of 10 preprints.
The Longevist - our expert team of Longevist Curators vote “on-chain” on The Longevist Snapshot page by connecting their crypto wallet and selecting the preprints which they think are the most impactful. The entire shortlist of 10 preprints is then featured in an issue of the Longevist in rank order based on the number of Curator votes received, with the top 3 voted preprints awarded “Curators' Choice” status.
Nominate a preprint and you will be rewarded with 50 $VITA if it makes the editors' shortlist and 200 $VITA if it is voted in the top 3 by our team of expert Curators. Find out more about the VITA token here.
A team of biology/longevity PhDs who are all active VitaDAO contributors. Meet us and the rest of the team just above this FAQs section.
Our Curators are a mix of industry & academic experts in the longevity space, consisting of new group leaders to leading professors, communicators, and founders. We are always looking for new Curators - if you would like to nominate yourself or someone else, please get in touch! Curators are currently compensated with 500 $VITA per issue they vote on.
A blockchain is a distributed database or ledger shared among a computer network's nodes. We put both the curator vote and the preprint articles on the blockchain for transparency and permanence, as blockchains are significantly more open, robust and secure for information storage than centralized databases.
You can sign up to "Stay Updated" at the bottom right of The Longevist homepage. We are also active on Twitter @longevist_xyz.
No, we are not modifying the content from the original preprint. We are simply curating the best preprints each quarter to increase visibility on impactful research.
The Longevist promotes research which has the potential to have the largest impact on improving human healthspan and lifespan. Our definition includes research which tackles both the underlying causes of aging and age-related diseases.
The Longevity Decentralised Review (TLDR) is a VitaDAO initiative to provide compensation for peer reviews. We are currently offering a bounty of 50 $VITA for reviewing any of the preprints featured in The Longevist. Only those who have left a review, as well as authors of the preprint are permitted to see the reviews for that preprint.
Desci Nodes is a next-generation open-science solution for researchers who want to publish and manage manuscripts, data, code, and all other artefacts of research. With permission, the Longevist uploads preprints to Nodes, as it provides an on-chain mechanism that is open source and maintainable by decentralized, as opposed to closed source, networks.
VitaDAO is a community-owned collective dedicated to funding and advancing longevity science research that can improve people's lives. VitaDAO also supports numerous initiatives, including The Longevity Decentralized Review, The VitaDAO Longevity Fellowship and The Longevist.
Please direct editorial enquiries to Tim Peterson or Rhys Anderson.
